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IBL/Haemophilus influenzae B (HIB) IgG ELISA/RE56351/

  • 产品编号: RE56351
  • 美  元  价: $0.00
  • 会  员  价: 待定
  • 品       牌: IBL
  • 产       地: 美国
  • 公       司: IBL,inc
  • 产品分类: ref="." class="index">首页 > IBL/Haemophilus influenzae B (HIB) IgG ELISA/RE56351/
  • 公司分类: Infectious Diseases
IBL/Haemophilus influenzae B (HIB) IgG ELISA/RE56351/
  • IBL/Haemophilus influenzae B (HIB) IgG ELISA/RE56351/
商品介绍
Kit size12 x 8
MethodELISA
Incubation time2 x 1 h, 1 x 30min
Standard rangeLot specific
Specimen / Volumes20 µl Serum, Plasma
Substrate / isotopeTMB 450 nm
Regulatory Status:EU: CE, CDN: IVD
Details for:  Haemophilus influenzae B (HIB) IgG ELISA
Haemophilus influenzae type B (HiB) is a very common cause of invasive critical infectious diseases in children up to the age of six. Following infection the symptoms of the disease include: Pericarditis, osteomyelitis, meningitis, encephalitis, pneumonia, sinusitis and otitis. In many cases the disease is lethal or leads to neurological damage, which cannot always be prevented by rapid antibiotic therapy. The underlying reason for the disease is very often a latent immunodeficiency with a specifically reduced humoral immune response to the polyribosylribitolphosphate (PRP) in the polysaccharide encapsulation of the bacterium. In children another reason is the immaturity of the immune system. Today often the term "immunocompromised patients" is used, comprising all acquired and innate specific and unspecific immunodeficiencies.
As a result, in children of 3 months of age or older a vaccination with different sorts of PRP-containing vaccines is recommended. This can lead to a clear reduction in the number of infections with Haemophilus influenzae type B.
The titer of antibodies produced by vaccination can be used to confirm whether the vaccination has been successful. The HiB IgG is used to measure the level of PRP-specific IgG-antibodies following a 4 6 week period after complete immunization to monitor the humoral immune status of children or other individuals at risk.
Monitoring of the humoral immunostatus after vaccination. Verification of the diagnosis Haemophilus influenzae type B infection by repeated monitoring of antibody concentrations. Risk assessment in immunocompromised patients leADIng to a failure of vaccination with a PRP-containing vaccine.
This group comprises:
Children under 2 years having had an infection with Haemophilus influenzae type B,
Children with chronic, recurring bacterial infections of the respiratory tract,
Children with chronic otitis,
Patients with confirmed humoral immuno-deficiencies (IgG-2-deficiency, IgA-deficiency),
Patients with confirmed granulocyte deficiencies,
Patients under chemo or cytostatic therapy,
Children after splenectomy,
Patients with sickle-cell anaemia,
Patients with trisomy 21 (Down) syndrome, and certain ethnic groups.
For concrete data please consult the Instruction for Use in the download box on the right side.
品牌介绍

IBL International – part of the Tecan Group – is an expert diagnostics provider focusing on special and rare indications. The company has over 30 years of experience in the development, manufacture and supply of immunoassays – including enzyme, radiolabeled, and luminescence-based assays – for research and routine diagnostics.We are a pioneer and market leader in saliva diagnostics, offering a broad portfolio of luminescence- and ELISA-based tests for analytes such as cortisol, testosterone, estriol and various interleukins. The company also offers a number of specialist diagnostic assays for Endocrinology, neurotransmitters and Infectious disease in clinical diagnostics, along with key assays for the research segment, including HMGB1 and NF Light . By combining IBL International’s immunodiagnostics expertise with Tecan’s long tradition in serving the clinical diagnostic market, many of these assays have been specifically optimized for fully automated processing on the Freedom EVOlyzer® or Freedom EVO® platforms, offering complete solutions for the biochemical diagnosis.
IBL International products are available worldwide, through dedicated Tecan sales teams in the US, Europe and China, as well as an extensive distributor network and worldwide support from Tecan's regional offices. An experienced team of product managers and customer service staff ensure the rapid support necessary in a clinical environment, and the company's active research and development program has close ties with academic centers and commercial partners around the world.All the company’s assays have been designed with uniform pipetting procedures and shared reagents – offering easy adaptation for automated Tecan liquid handling platforms – and are manufactured to meet the highest global regulatory requirements and quality standards. IBL International is certified under ISO 9001, ISO 13485 and CMDCAS, meets GMP regulations and is audited by the US FDA. Combining these high quality assays with Tecan’s flexible automated solutions offers exceptional productivity, throughput and reproducibility for clinical diagnostics and research.

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